Climate and environmental conditions are increasingly recognized as key determinants of population health, with disproportionate impacts on women across different geographic regions. Women are often more vulnerable to environmental stressors due to biological, social, and economic factors. This study aims to examine the global-scale relationships between climate parameters, air quality, landforms, and topography, and their combined effects on women’s health and wellbeing. The research adopts a macro-level and spatially explicit approach using Geographic Information Systems (GIS) and remote sensing data. Multiple climate variables, including temperature, precipitation, humidity, and heat stress indices, are integrated with global air quality indicators such as particulate matter and nitrogen dioxide. In addition, landform classification and topographic features, including elevation, slope, and terrain complexity, are analyzed to assess their role in shaping environmental exposure.
Global thematic maps are produced to identify spatial patterns, regional disparities, and clusters of high environmental risk. The results reveal strong spatial variability in climate-related and air pollution exposure among women. Regions characterized by extreme temperatures, poor air quality, and complex topography show higher levels of health vulnerability. Topographic conditions are found to influence pollutant accumulation, heat retention, and accessibility to health resources, thereby modifying health outcomes. The findings highlight that environmental risks and gender-based health inequalities are closely interconnected at the global scale. Women living in climate-sensitive and low-resource regions face compounded risks that directly affect physical health, mental wellbeing, and quality of life. This study emphasizes the importance of incorporating spatial, climatic, and topographic perspectives into women’s health research and public health planning. The proposed framework supports evidence-based decision-making and contributes to the development of climate-resilient and gender-responsive health policies worldwide.